San Antonio Hotel Hersonissos is situated a mere 0.7 km from Aquaworld Aquarium & Reptile Rescue Centre and features a terrace and a garden. The hotel offers 6 rooms with views of the garden.

The property is merely 500 metres from Quad Safari, with Unoficial FKK Naturist Beach around 10 minutes away by car. Starmate Art & Accessories Swimwear Store is a short way from this 2-star hotel in Hersonissos. A golden-sandy beach is about a 5-minute walk from the accommodation, while Labyrinth Park is situated nearly 10 minutes away by car. The nearby sports attractions feature The Crete Golf Club 10 minutes' drive away San Antonio Hotel. This property is also just a minute's drive from Do Zeus hotel bus stop.

The accommodation offers rooms with a balcony and a dressing room featuring ironing facilities and air conditioning, along with a flat-screen TV with satellite channels. They come equipped with an electric kettle, a refrigerator, and an oven. Featuring a bathtub, a separate toilet, and a shower, the bathrooms also have a hair dryer and bathrobes.

Guests can dine at the café Coffee Island located about 5 minutes' walk away.