Offering a seasonal outdoor swimming pool and views of the city, Melitti Hotel Rethymno is situated 5 minutes' walk from the Church of Our Lady of Angels. This aparthotel features Wi-Fi in public areas and public parking nearby.

The Rethymnon Old Town is 2.6 km from the 4-star hotel, while the 17th-century Venetian Rimondi Fountain is 2.7 km away. The Melitti is conveniently located within a 100-metre distance of a small beach. This property offers a quiet location next to a mini-mart, bakeries, and a market. The smoke-free hotel is a 25-minute stroll from Misiria. Perivolia bus stop lies 750 metres away.

Furnished with a writing desk, the 33 rooms also include such conveniences as complimentary wireless internet and a flat-screen TV with satellite channels, along with coffee and tea making equipment. They offer couch beds in the bedrooms. Bathrooms are fitted with a separate toilet and a shower as well as hair dryers and free toiletries.

Melitti Hotel features a buffet breakfast daily. Guests may find the restaurant CopaCabana Beach Bar a 5-minute walk away.